PROJECT TITLE :

Temporal Sparse Promoting Three Dimensional Imaging of Cardiac Activation

ABSTRACT:

A replacement Cardiac Electrical Sparse Imaging (CESI) technique is proposed to image cardiac activation throughout the three-dimensional myocardium from body surface electrocardiogram (ECG) with the help of individualized heart-torso geometry. The sparse property of cardiac electrical activity within the time domain is utilised in the temporal sparse promoting inverse solution, one formulated to realize higher spatial-temporal resolution, stronger robustness and therefore enhanced capability in imaging cardiac electrical activity. Pc simulations were allotted to judge the performance of this imaging method underneath numerous circumstances. A complete of twelve single web site pacing and seven twin sites pacing simulations with artificial and therefore the hospital recorded sensor noise were used to judge the accuracy and stability of the proposed methodology. Simulations with modeling error on heart-torso geometry and electrode-torso registration were additionally performed to evaluate the robustness of the technique. Plus the computer simulations, the CESI algorithm was more evaluated using experimental data in an animal model where the noninvasively imaged activation sequences were compared with those measured with simultaneous intracardiac mapping. All of the CESI results were compared with standard weighted minimum norm solutions. This results show that CESI can image with better accuracy, stability and stronger robustness in each simulated and experimental circumstances. In sum, we tend to have proposed a completely unique method for cardiac activation imaging, and our results recommend that the CESI has enhanced performance, and offers the potential to image the cardiac activation and to assist within the clinical management of ventricular arrhythmias.